THE ENZYMATIC SYNTHESIS OF GLUTAMINE, A REACTION UTILIZING ADENOSINE TRIPHOSPHATE
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چکیده
منابع مشابه
The enzymatic synthesis of glutamine, a reaction utilizing adenosine triphosphate.
The preceding paper (2) describes experiments on the synthesis of glutamine in pigeon liver dispersions, which, together with the results of Krebs and his collaborators (3, 4) and of Bujard and Leuthardt (5), suggested that adenosine triphosphate may play an essential r81e in amide formation. Proof for this function of adenosine triphosphate has been obt.ained in studies with tissue extracts, w...
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Glutamine establishes feedback control of glutamine synthetase (EC 6.3.1.2) in Escherichia coli over a novel loop, viz. by its effect on an enzymatic adenylylation of glutamine synthetase, whose activity is thus modulated. Positive effecters of the adenylyl transfer reaction, magnesium ion and glutamine, increase the number of -SH groups in adenylyltransferase (EC 2.7.7. -) titratable by 5,5’-d...
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Previous reports from this laboratory have demonstrated that the ATP-Pi32 1 exchange reaction (1) and the dinitrophenolstimulated ATPase activity (2) of mitochondrial subfragments (3-9) are reflections of intermediate enzymatic steps in the complex sequence of reactions (1, 3) in which phosphorylation of ADP is coupled to electron transport in the respiratory chain. This communication concerns ...
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1. A study is made of the effect of adenosine triphosphate (ATP) upon the viscosity of solutions of actomyosin in 0.5 M KCl. 2. The observed effects are discussed in terms of an initial drop of the viscosity (viscosity response) and its subsequent slow reversal (recovery effect). The latter is ascribed to a decrease in the ATP concentration through enzymatic hydrolysis. 3. The recovery effect i...
متن کاملStudies on the Enzymatic Synthesis of Glutamine.
Theorell (1942) has reported sedimentation and diffusion measurements on peroxidase: our value for S20 (corr.) is about 10% lower than his (3-85 x 10-13) (cf. Cecil & Ogston, 1948), while our value for D20 (corr.) agrees fairly well with his value of 6 84 x 1o-7. Our value for the molecular weight is lower than Theorell's (44,100), but is in agreement with that calculated by Keilin & Hartree (1...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1949
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)56802-2